Article
Prediction by pharmacogenetics of safety and efficacy of non-steroidal anti- inflammatory drugs: a review.
Current drug metabolism - 1 Mar 2014
Rollason Victoria, Samer Caroline Flora, Daali Youssef, Desmeules Jules Alexandre
Abstract excerpt
Non-steroidal anti-inflammatory drugs (NSAIDs) are the most frequently used drugs, either on prescription or over-thecounter (OTC). Their daily dosage is based on randomised controlled trials and an empirical clinical assessment of their efficacy and toxicity that allows dose adjustment. The individual response can however be altered by environmental and genetic pharmacokinetic and pharmacodynamic factors. This...
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