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Article

HABP2 p.G534E variant in patients with family history of thyroid and breast cancer.

Oncotarget - 20 Jun 2017

Pinheiro Maisa, Drigo Sandra Aparecida, Tonhosolo Renata, Andrade Sonia C S, Marchi Fabio Albuquerque, Jurisica Igor, Kowalski Luiz Paulo, Achatz Maria Isabel, Rogatto Silvia Regina

Abstract excerpt

Familial Papillary Thyroid Carcinoma (PTC) has been described as a hereditary predisposition cancer syndrome associated with mutations in candidate genes including HABP2. Two of 20 probands from families with history of PTC and breast carcinoma (BC) were evaluated by whole exome sequencing (WES) revealing HABP2 p.G534E. Sanger sequencing was used to confirm the involvement of this variant in three families (F1: 7...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28402931
DOI: 10.18632/oncotarget.16639
PMCID: PMC5522276

Genes

HABP2
CTSB
LOXL2
MMP11
MSH2
MUSK
NBN
NID1
TNXB
TRIM24

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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