Article
Constitutional 3p26.3 terminal microdeletion in an adolescent with neuroblastoma.
Cancer biology & therapy - 4 May 2017
Pezzolo Annalisa, Sementa Angela Rita, Lerone Margherita, Morini Martina, Ognibene Marzia, Defferrari Raffaella, Mazzocco Katia, Conte Massimo, Gigliotti Anna Rita, Garaventa Alberto, Pistoia Vito, Varesio Luigi
Abstract excerpt
BACKGROUND: Neuroblastoma (NB) is a common and often lethal cancer of early childhood that accounts for 10% of pediatric cancer mortality. Incidence peaks in infancy and then rapidly declines, with less than 5% of cases diagnosed in children and adolescents ≥ 10 y. There is increasing evidence that NB has unique biology and an chronic disease course in older children and adolescents, but ultimately dismal...
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