Article
Presence of the IVS-I-6-Mutated Allele in Beta-Thalassemia Major Patients Correlates with Extramedullary Hematopoiesis Incidence.
Acta haematologica - 1 Jan 2017
Sousos Nikolaos, Adamidou Despoina, Klonizakis Philippos, Agapidou Alexandra, Theodoridou Stamatia, Spanos Georgios, Psarras Kyriakos, Vetsiou Evaggelia, Vyzantiadis Timoleon-Achilleas, Vlachaki Efthymia
Abstract excerpt
Extramedullary hematopoiesis (EMH) results from the extension of hematopoietic tissue beyond the confines of the bones. Since the initiation of regular transfusion programs from an early age for all thalassemia major (ΤΜ) patients, EMH has not been considered a clinical issue anymore. The present study aims to record the prevalence of EMH in chronically transfused ΤΜ patients followed at our institution and to...
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