Article
Analysis of beta-thalassemia mutations in the United Arab Emirates provides evidence for recurrent origin of the IVSI nt 5 (G-C) mutation.
Human mutation - 1 Jan 1995
De Leo R, Deidda G, Novelletto A, el-Kalla S, Mathews A R, Felicetti L
Abstract excerpt
Beta-thalassemia mutations were characterized in a sample of 70 patients from United Arab Emirates (U.A.E.), resulting in an enlargement of the spectrum of types found in the country. The complete association between the most common IVS I nt 5 (G-C) mutation and a specific haplotype reveals an independent origin of this mutation in U.A.E.
Topics
- DNA Mutational Analysis
- Haplotypes
- Humans
- Mutation
- Recurrence
- United Arab Emirates
- beta-Thalassemia