Article
Possible factors influencing the haemoglobin and fetal haemoglobin levels in patients with beta-thalassaemia due to a homozygosity for the IVS-I-6 (T-->C) mutation.
British journal of haematology - 1 Apr 1994
Efremov D G, Dimovski A J, Baysal E, Ye Z, Adekile A D, Ribeiro M L, Schiliro G, Altay C, Gürgey A, Efremov G D
Abstract excerpt
We have collected haematological, haemoglobin (Hb) and DNA sequence data for 29 patients with a homozygosity for the IVS-I-6 (T-->C) mutation with the intention of identifying factors contributing to the observed variability in the severity of the disease. None of the patients had received blood...
Topics
- Adolescent
- Adult
- Base Sequence
- Child
- Child, Preschool
- Female
- Fetal Hemoglobin
- Globins
- Hemoglobin A2
- Hemoglobins
- Homozygote
- Humans
- Male
- Middle Aged
- Molecular Sequence Data