Article
Hydroxyurea-induced hematological response in transfusion-independent beta-thalassemia intermedia: case series and review of literature.
Pediatric hematology and oncology - 1 Nov 2009
Ehsani Mohammad Ali, Hedayati-Asl Amir Abbas, Bagheri Alireza, Zeinali Syrus, Rashidi Armin
Abstract excerpt
BACKGROUND: Hydroxyurea (HU) may improve the symptoms in thalassemia patients by increasing gamma-globin chain expression. However, the efficacy of HU in beta-thalassemia intermedia (TI) is unclear. METHODS: The authors treated 16 transfusion-independent TI patients (8 males) aged 10.7 +/- 5.0 ye...
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