KRAS mutations detection methodology: from RFLP to CRISPR/Cas based methods.

Abstract excerpt

In personalized cancer medicine, the identification of KRAS mutations is essential for making treatment decisions and improving patient outcomes. This work presents a comprehensive review of the current approaches for detection of KRAS mutations in different cancers. We highlight the value of fast and reliable KRAS mutations discovery and the effectiveness of molecular testing for selecting individuals who might...

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• CRISPR-Cas Systems
• High-Throughput Nucleotide Sequencing
• Mutation
• Neoplasms
• Proto-Oncogene Proteins p21(ras)