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Article

A meta-analysis of association between C677T polymorphism in the methylenetetrahydrofolate reductase gene and hypertension.

European journal of human genetics : EJHG - 1 Dec 2007

Qian Xueqing, Lu Zhigang, Tan Miao, Liu Hongliang, Lu Daru

Abstract excerpt

The C677T polymorphism of the methylenetetrahydrofolate reductase (MTHFR) gene was implicated to be associated with hypertension due to its role in catalyzing the formation of 5-methylenetetrahydrofolate, a co-substrate for the conversion of homocysteine to methionine. Association studies were reported in different populations; however, a great number of subsequent studies have produced contrary results, possibly...

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Source

Identifiers

PMID: 17726486
DOI: 10.1038/sj.ejhg.5201914

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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