Article
A meta-analysis of association between C677T polymorphism in the methylenetetrahydrofolate reductase gene and hypertension.
European journal of human genetics : EJHG - 1 Dec 2007
Qian Xueqing, Lu Zhigang, Tan Miao, Liu Hongliang, Lu Daru
Abstract excerpt
The C677T polymorphism of the methylenetetrahydrofolate reductase (MTHFR) gene was implicated to be associated with hypertension due to its role in catalyzing the formation of 5-methylenetetrahydrofolate, a co-substrate for the conversion of homocysteine to methionine. Association studies were re...
Topics
- Asian People
- Bias
- Cytosine
- Genetic Predisposition to Disease
- Heterozygote
- Humans
- Hypertension
- Methylenetetrahydrofolate Reductase (NADPH2)
- Odds Ratio
- Polymorphism, Single Nucleotide
- Risk Factors
- Thymine
- White People