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Article

Association Between Functional Nucleotide Polymorphisms Up-regulating Transforming Growth Factor β1 Expression and Increased Tuberculosis Susceptibility.

The Journal of infectious diseases - 2 Mar 2022

Zhang Su, Li Guobao, Bi Jing, Guo Qinglong, Fu Xiangdong, Wang Wenfei, Liu Shuyan, Xiao Guohui, Ou Min, Zhang Juanjuan, He Xing, Li Fang, Li Guanqiang, Feng Carl G, Chen Xinchun, Zhang Guoliang

Abstract excerpt

Previous studies demonstrated that transforming growth factor (TGT) β1 plays an immunosuppressive role in clinical tuberculosis. However, the contribution of TGF-β1 gene polymorphisms to human tuberculosis susceptibility remains undetermined. In this study, we showed that single-nucleotide polymorphisms (SNPs) in TGF-β1 gene were associated with increased susceptibility to tuberculosis in the discovery cohort...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32939551
DOI: 10.1093/infdis/jiaa585
PMCID: PMC8889291

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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