Article
Polymorphisms and haplotypes of the TGF-β1 gene are associated with risk of polycystic ovary syndrome in Chinese Han women.
European journal of obstetrics, gynecology, and reproductive biology - 1 Mar 2015
Yang Jie, Zhong Ting, Xiao Guohong, Chen Yan, Liu Jianqiao, Xia Chenglai, Du Hongzi, Kang Xiangjin, Lin Yuyi, Guan Ronghua, Yan Pengke, Xiao Jianhua
Abstract excerpt
OBJECTIVES: Transforming growth factor-beta 1 (TGF-β1) is one of the multifunctional cytokine families. It takes part in a series of physiological and pathological processes in the human body, including wound healing, tissue fibrosis and embryonic development. Recent studies have shown that TGF-β1 participates in the development of polycystic ovary syndrome (PCOS). This study was therefore designed to investigate...
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