Article
Novel alleles of the transforming growth factor β-1 regulatory region and exon 1.
Tissue antigens - 1 Jun 2015
Arrieta-Bolaños E, Madrigal J A, Shaw B E
Abstract excerpt
Transforming growth factor β-1, encoded by the TGFB1 gene, is a cytokine that plays a central role in many physiologic and pathogenic processes with pleiotropic effects. Regulatory activity for this gene has been shown for 3.0 kb between positions -2665 and +423 from its translational start site. At least 17 TGFB1 regulatory region and exon 1 alleles have been defined on the basis of 18 polymorphic sites....
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