Article
Adipose Tissue Macrophages in Rheumatoid Arthritis: Prevalence, Disease-Related Indicators, and Associations With Cardiometabolic Risk Factors.
Arthritis care & research - 1 Feb 2018
Giles Jon T, Ferrante Antony W, Broderick Rachel, Zartoshti Afshin, Rose Janine, Downer Kendall, Zhang Hui-Zhu, Winchester Robert J
Abstract excerpt
OBJECTIVE: Adipose tissue macrophages (ATMs) are a potent source of inflammatory cytokines, with profound effects on adipose tissue function, yet their potential role in rheumatoid arthritis (RA) pathobiology is largely unstudied. METHODS: Periumbilical subcutaneous adipose tissue was obtained from 36 RA patients and 22 non-RA controls frequency matched on demographics and body mass index. Samples were stained...
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