Article
A 3q gene signature associated with triple negative breast cancer organ specific metastasis and response to neoadjuvant chemotherapy.
Scientific reports - 7 Apr 2017
Qian Jun, Chen Heidi, Ji Xiangming, Eisenberg Rosana, Chakravarthy A Bapsi, Mayer Ingrid A, Massion Pierre P
Abstract excerpt
Triple negative breast cancers (TNBC) are aggressive tumors, with high rates of metastatic spread and targeted therapies are critically needed. We aimed to assess the prognostic and predictive value of a 3q 19-gene signature identified previously from lung cancer in a collection of 4,801 breast tumor gene expression data. The 3q gene signature had a strong association with features of aggressiveness such as high...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.