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Article

Genome-wide hepatic DNA methylation changes in high-fat diet-induced obese mice

1 Jan 2017

Abstract excerpt

BACKGROUND/OBJECTIVES: A high-fat diet (HFD) induces obesity, which is a major risk factor for cardiovascular disease and cancer, while a calorie-restricted diet can extend life span by reducing the risk of these diseases. It is known that health effects of diet are partially conveyed through epigenetic mechanism including DNA methylation. In this study, we investigated the genome-wide hepatic DNA methylation to...

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PMID: 28386383
DOI: 10.4162/nrp.2017.11.2.105

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