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Article

Intestinal IgA as a modulator of the gut microbiota

6 Apr 2017

Abstract excerpt

Accumulating evidence suggests that dysbiosis plays a role in the pathogenesis of intestinal diseases including inflammatory bowel disease (IBD) as well as extra-intestinal disorders. As a modulator of the intestinal microbiota, we isolated a mouse monoclonal IgA antibody (clone W27) with high affinities for multiple commensal bacteria, but not for beneficial bacteria such as Lactobacillus casei (L. casei). Via...

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Identifiers

PMID: 28384049
DOI: 10.1080/19490976.2017.1310357

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