Article
Low-depth genotyping-by-sequencing (GBS) in a bovine population: strategies to maximize the selection of high quality genotypes and the accuracy of imputation.
BMC genetics - 5 Apr 2017
Brouard Jean-Simon, Boyle Brian, Ibeagha-Awemu Eveline M, Bissonnette Nathalie
Abstract excerpt
BACKGROUND: Genotyping-by-sequencing (GBS) has emerged as a powerful and cost-effective approach for discovering and genotyping single-nucleotide polymorphisms. The GBS technique was largely used in crop species where its low sequence coverage is not a drawback for calling genotypes because inbred lines are almost homozygous. In contrast, only a few studies used the GBS technique in animal populations (with...
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