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Article

Osteocyte Protein Expression Is Altered in Low-Turnover Osteoporosis Caused by Mutations in WNT1 and PLS3.

The Journal of clinical endocrinology and metabolism - 1 Jul 2017

Wesseling-Perry Katherine, Mäkitie Riikka E, Välimäki Ville-Valtteri, Laine Tero, Laine Christine M, Välimäki Matti J, Pereira Renata C, Mäkitie Outi

Abstract excerpt

Context: Osteocytes express proteins that regulate bone remodeling and mineralization. Objective: To evaluate the relationship between osteocyte-specific protein expression and bone histology in patients with monogenic osteoporosis due to wingless integration site 1 (WNT1) or plastin 3 (PLS3) mutations. Design and Setting: Cross-sectional cohort study at a university hospital. Participants: Six patients (four...

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Source

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Identifiers

PMID: 28379384
DOI: 10.1210/jc.2017-00099
PMCID: PMC5505188

Genes

PLS3
WNT1
DMP1
FGF23

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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