Article
AD-LIBS: inferring ancestry across hybrid genomes using low-coverage sequence data.
BMC bioinformatics - 4 Apr 2017
Schaefer Nathan K, Shapiro Beth, Green Richard E
Abstract excerpt
BACKGROUND: Inferring the ancestry of each region of admixed individuals' genomes is useful in studies ranging from disease gene mapping to speciation genetics. Current methods require high-coverage genotype data and phased reference panels, and are therefore inappropriate for many data sets. We present a software application, AD-LIBS, that uses a hidden Markov model to infer ancestry across hybrid genomes...
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