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Article

Accurate detection of identity-by-descent segments in human ancient DNA.

Nature genetics - 1 Jan 2024

Ringbauer Harald, Huang Yilei, Akbari Ali, Mallick Swapan, Olalde Iñigo, Patterson Nick, Reich David

Abstract excerpt

Long DNA segments shared between two individuals, known as identity-by-descent (IBD), reveal recent genealogical connections. Here we introduce ancIBD, a method for identifying IBD segments in ancient human DNA (aDNA) using a hidden Markov model and imputed genotype probabilities. We demonstrate that ancIBD accurately identifies IBD segments >8 cM for aDNA data with an average depth of >0.25× for whole-genome...

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Identifiers

PMID: 38123640
DOI: 10.1038/s41588-023-01582-w
PMCID: PMC10786714

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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