Article
diempy: fast and reference-free genome polarisation
2026-02-19
Abstract excerpt
Most ancestry-assignment methods rely on putatively pure reference panels, which are often unrealistic and bias inference. The genome polarisation algorithm diem , introduced previously, avoids reference panels by jointly inferring the polarity of common allelic states and quantifying variant diagnosticity via an expectation–maximisation procedure. Here we present diempy , an efficient python implementation of...
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Identifiers and source
- Literature Corpus work
- 0c21c259-24e1-5a0b-b18f-296c93ae0134
- DOI
- 10.64898/2026.02.18.706591