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Article

Analysis of PTPN22 C1858T gene polymorphism in cases with type 1 diabetes of Azerbaijan, Northwest Iran.

Cellular immunology - 1 Jan 2000

Almasi Shohreh, Aliparasti Mohammad Reza, Yazdchi-Marandi Leili, Aliasgarzadeh Akbar, Sioofy-Khojine Amirbabak, Mesri Adel, Zamani Fatemeh

Abstract excerpt

BACKGROUND: Type 1 diabetes (T1D) is a T-cell mediated autoimmune multifactorial disease. The PTPN22 gene encodes an intracellular lymphoid-specific phosphatase (Lyp) that has been shown to play a negative regulatory role in T cell activation. OBJECTIVES: The aim of the present study was to find out associating the PTPN22 C1858T (R620W) polymorphism and T1D in the Azeri population from Northwest Iran. SUBJECTS...

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Adolescent
Child
Diabetes Mellitus, Type 1
Iran
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Protein Tyrosine Phosphatase, Non-Receptor Type 22

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Identifiers

PMID: 25243643
DOI: 10.1016/j.cellimm.2014.08.007

Genes

PTPN22

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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Analysis of PTPN22 C1858T gene polymorphism in cases with type 1 diabetes of Azerbaijan, Northwest Iran.PMID 25243643Read ↗

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The Potential Role of PTPN-22 C1858T Gene Polymorphism in the Pathogenesis of Type 1 Diabetes in Saudi Population.Semantic proximity Read ↗

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The protein tyrosine phosphatase non-receptor type 22 C1858T polymorphism is a joint susceptibility locus for immunthyroiditis and autoimmune diabetes.Semantic proximity Read ↗

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C1858T Polymorphism of Protein Tyrosine Phosphatase Non-receptor Type 22 (PTPN22): an eligible target for prevention of type 1 diabetes?Semantic proximity Read ↗

Susceptibility to type 1 diabetes conferred by the PTPN22 C1858T polymorphism in the Spanish population.Semantic proximity Read ↗

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