Article
Brain-derived neurotrophic factor Val66Met genotype modulates amygdala habituation.
Psychiatry research. Neuroimaging - 30 May 2017
Perez-Rodriguez M Mercedes, New Antonia S, Goldstein Kim E, Rosell Daniel, Yuan Qiaoping, Zhou Zhifeng, Hodgkinson Colin, Goldman David, Siever Larry J, Hazlett Erin A
Abstract excerpt
A deficit in amygdala habituation to repeated emotional stimuli may be an endophenotype of disorders characterized by emotion dysregulation, such as borderline personality disorder (BPD). Amygdala reactivity to emotional stimuli is genetically modulated by brain-derived neurotrophic factor (BDNF) variants. Whether amygdala habituation itself is also modulated by BDNF genotypes remains unknown. We used...
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