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Article

Combinatorial synthesis of genetic networks.

Science (New York, N.Y.) - 24 May 2002

Guet Călin C, Elowitz Michael B, Hsing Weihong, Leibler Stanislas

Abstract excerpt

A central problem in biology is determining how genes interact as parts of functional networks. Creation and analysis of synthetic networks, composed of well-characterized genetic elements, provide a framework for theoretical modeling. Here, with the use of a combinatorial method, a library of networks with varying connectivity was generated in Escherichia coli. These networks were composed of genes encoding the...

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PMID: 12029133
DOI: 10.1126/science.1067407

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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