Article
Genetic Diversity within Alphaherpesviruses: Characterization of a Novel Variant of Herpes Simplex Virus 2.
Journal of virology - 1 Dec 2015
Burrel Sonia, Désiré Nathalie, Marlet Julien, Dacheux Laurent, Seang Sophie, Caumes Eric, Bourhy Hervé, Agut Henri, Boutolleau David
Abstract excerpt
UNLABELLED: Very low levels of variability have been reported for the herpes simplex virus 2 (HSV-2) genome. We recently described a new genetic variant of HSV-2 (HSV-2v) characterized by a much higher degree of variability for the UL30 gene (DNA polymerase) than observed for the HG52 reference strain. Retrospective screening of 505 clinical isolates of HSV-2 by a specific real-time PCR assay targeting the UL30...
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