Article
Using HSV-1 genome phylogenetics to track past human migrations.
PloS one - 1 Jan 2013
Kolb Aaron W, Ané Cécile, Brandt Curtis R
Abstract excerpt
We compared 31 complete and nearly complete globally derived HSV-1 genomic sequences using HSV-2 HG52 as an outgroup to investigate their phylogenetic relationships and look for evidence of recombination. The sequences were retrieved from NCBI and were then aligned using Clustal W. The generation of a maximum likelihood tree resulted in a six clade structure that corresponded with the timing and routes of past...
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