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Article

Evolution and diversity in human herpes simplex virus genomes.

Journal of virology - 1 Jan 2014

Szpara Moriah L, Gatherer Derek, Ochoa Alejandro, Greenbaum Benjamin, Dolan Aidan, Bowden Rory J, Enquist Lynn W, Legendre Matthieu, Davison Andrew J

Abstract excerpt

Herpes simplex virus 1 (HSV-1) causes a chronic, lifelong infection in >60% of adults. Multiple recent vaccine trials have failed, with viral diversity likely contributing to these failures. To understand HSV-1 diversity better, we comprehensively compared 20 newly sequenced viral genomes from China, Japan, Kenya, and South Korea with six previously sequenced genomes from the United States, Europe, and Japan. In...

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Identifiers

PMID: 24227835
DOI: 10.1128/JVI.01987-13
PMCID: PMC3911644

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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