Article
Extensive genome-wide variability of human cytomegalovirus in congenitally infected infants.
PLoS pathogens - 1 May 2011
Renzette Nicholas, Bhattacharjee Bornali, Jensen Jeffrey D, Gibson Laura, Kowalik Timothy F
Abstract excerpt
Research has shown that RNA virus populations are highly variable, most likely due to low fidelity replication of RNA genomes. It is generally assumed that populations of DNA viruses will be less complex and show reduced variability when compared to RNA viruses. Here, we describe the use of high throughput sequencing for a genome wide study of viral populations from urine samples of neonates with congenital human...
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