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Article

Ganglioside and related-sphingolipid profiles are altered in a cellular model of Alzheimer's disease.

Biochimie - 1 Jun 2017

Noel Anastasia, Ingrand Sabrina, Barrier Laurence

Abstract excerpt

Sphingolipid-related issues are increasingly discussed to contribute to the neuropathological process of Alzheimer's disease (AD). In this study, gangliosides and related-sphingolipids (ceramides, neutral glycosphingolipids and sphingomyelins) were analyzed in neuroglioma (H4) cells expressing the Swedish mutation of the human amyloid precursor protein (H4APPsw) and compared with those of wild-type control H4...

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Identifiers

PMID: 28365364
DOI: 10.1016/j.biochi.2017.03.019

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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