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Article

Genotype-related changes of ganglioside composition in brain regions of transgenic mouse models of Alzheimer's disease.

Neurobiology of aging - 1 Dec 2007

Barrier Laurence, Ingrand Sabrina, Damjanac Milena, Rioux Bilan Agnès, Hugon Jacques, Page Guylène

Abstract excerpt

In this study, brain gangliosides of different transgenic mouse models of Alzheimer's disease (AD) were analyzed and compared with age-matched wild-type mice. Gangliosides were analyzed in cerebral cortex, a region with extensive A beta plaques, and cerebellum, a non-vulnerable region with no A beta containing plaques. There was a marked increase in simple gangliosides GM2 and GM3 only within the cortex of all...

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PMID: 17007963
DOI: 10.1016/j.neurobiolaging.2006.08.002

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APP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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