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Article

Pharmacogenetics of inflammatory bowel disease: a focus on Crohn's disease.

Pharmacogenomics - 1 Jul 2017

Rufini Sara, Ciccacci Cinzia, Novelli Giuseppe, Borgiani Paola

Abstract excerpt

Crohn's disease is an inflammatory bowel disease showing a high heterogeneity in phenotype and a strong genetic component. The treatment is complex, due to different severity of clinical parameters and to the fact that therapies only permit to control symptoms and to induce remission for short periods. Moreover, all categories of drugs present a great interindividual variability both in terms of efficacy and side...

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PMID: 28686143
DOI: 10.2217/pgs-2017-0068

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