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SCGB1D2 inhibits growth of Borrelia burgdorferi and affects susceptibility to Lyme disease

19 Mar 2024

Abstract excerpt

Lyme disease is a tick-borne disease caused by bacteria of the genus Borrelia. The host factors that modulate susceptibility for Lyme disease have remained mostly unknown. Using epidemiological and genetic data from FinnGen and Estonian Biobank, we identify two previously known variants and an unknown common missense variant at the gene encoding for Secretoglobin family 1D member 2 (SCGB1D2) protein that...

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PMID: 38503741
DOI: 10.1038/s41467-024-45983-9

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