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Article

Evolutionary perspectives on the links between mitochondrial genotype and disease phenotype.

Biochimica et biophysica acta - 1 Apr 2014

Dowling Damian K

Abstract excerpt

BACKGROUND: Disorders of the mitochondrial respiratory chain are heterogeneous in their symptoms and underlying genetics. Simple links between candidate mutations and expression of disease phenotype typically do not exist. It thus remains unclear how the genetic variation in the mitochondrial genome contributes to the phenotypic expression of complex traits and disease phenotypes. SCOPE OF REVIEW: I summarize the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24246955
DOI: 10.1016/j.bbagen.2013.11.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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