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Article

Sequence analysis of pooled bacterial samples enables identification of strain variation in group A streptococcus.

Scientific reports - 31 Mar 2017

Weldatsadik Rigbe G, Wang Jingwen, Puhakainen Kai, Jiao Hong, Jalava Jari, Räisänen Kati, Datta Neeta, Skoog Tiina, Vuopio Jaana, Jokiranta T Sakari, Kere Juha

Abstract excerpt

Knowledge of the genomic variation among different strains of a pathogenic microbial species can help in selecting optimal candidates for diagnostic assays and vaccine development. Pooled sequencing (Pool-seq) is a cost effective approach for population level genetic studies that require large numbers of samples such as various strains of a microbe. To test the use of Pool-seq in identifying variation, we pooled...

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Share to Genetic Variation
Share to Genome, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to High-Throughput Nucleotide Sequencing

Share to INDEL Mutation

Share to Polymorphism, Single Nucleotide

Share to Sequence Analysis, DNA

Share to Streptococcus pyogenes

Source

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Identifiers

PMID: 28361960
DOI: 10.1038/srep45771
PMCID: PMC5374712

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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