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Comparison of genomic diversity between single and pooled <i>Staphylococcus aureus</i> colonies isolated from human colonisation cultures

2023-06-14

Abstract excerpt

The most common approach to sampling the bacterial populations within an infected or colonised host is to sequence genomes from a single colony obtained from a culture plate. However, it is recognized that this method does not capture the genetic diversity in the population. An alternative is to sequence a mixture containing multiple colonies (“pool-seq”), but this has the disadvantage that it is a non-homogeneous...

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Literature Corpus work
73f75e71-21a6-57d8-8598-fe6b4ffe6a9e
DOI
10.1101/2023.06.14.544959
Open publication

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Comparison of genomic diversity between single and pooled <i>Staphylococcus aureus</i> colonies isolated from human colonisation culturesDOI 10.1101/2023.06.14.544959
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