Article
Pharmacogenomics study on cadherin 2 network with regard to HIV infection and methadone treatment outcome.
PloS one - 1 Jan 2017
Kuo Hsiang-Wei, Shih Chia-Lung, Tsung Jieh-Hen, Liu Sheng-Wen, Chu Shih-Kai, Yang Hsin-Chou, Tsou Hsiao-Hui, Wang Zih-Hsiang, Chen Andrew C H, Liu Yu-Li
Abstract excerpt
Heroin dependent patients have a high incidence of HIV infection. In contrast to the gene expression method, we developed a systemic correlation analysis method built upon the results of pharmacogenomics study in a methadone maintenance treatment (MMT) cohort consisting of 344 Taiwanese heroin dependent patients. We identified genetic variants and their encoding proteins that may be involved with HIV infection...
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