Article
Integration of Molecular Inflammatory Interactome Analyses Reveals Dynamics of Circulating Cytokines and Extracellular Vesicle Long Non-Coding RNAs and mRNAs in Heroin Addicts During Acute and Protracted Withdrawal.
Frontiers in immunology - 1 Jan 2021
Zhang Zunyue, Wu Hongjin, Peng Qingyan, Xie Zhenrong, Chen Fengrong, Ma Yuru, Zhang Yizhi, Zhou Yong, Yang Jiqing, Chen Cheng, Li Shaoyou, Zhang Yongjin, Tian Weiwei, Wang Yuan, Xu Yu, Luo Huayou, Zhu Mei, Kuang Yi-Qun, Yu Juehua, Wang Kunhua
Abstract excerpt
Heroin addiction and withdrawal influence multiple physiological functions, including immune responses, but the mechanism remains largely elusive. The objective of this study was to investigate the molecular inflammatory interactome, particularly the cytokines and transcriptome regulatory network in heroin addicts undergoing withdrawal, compared to healthy controls (HCs). Twenty-seven cytokines were...
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