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Article

Whole-genome analysis of papillary kidney cancer finds significant noncoding alterations.

PLoS genetics - 1 Mar 2017

Li Shantao, Shuch Brian M, Gerstein Mark B

Abstract excerpt

To date, studies on papillary renal-cell carcinoma (pRCC) have largely focused on coding alterations in traditional drivers, particularly the tyrosine-kinase, Met. However, for a significant fraction of tumors, researchers have been unable to determine a clear molecular etiology. To address this, we perform the first whole-genome analysis of pRCC. Elaborating on previous results on MET, we find a germline SNP...

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Share to Carcinoma, Renal Cell
Share to Chromatin
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins c-met

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Source

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Identifiers

PMID: 28358873
DOI: 10.1371/journal.pgen.1006685
PMCID: PMC5391127

Genes

MET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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