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Article

Papillary renal cell carcinoma with a somatic mutation in MET in a patient with autosomal dominant polycystic kidney disease.

Cancer genetics - 1 Jan 2000

Zhang Wanying, Tan Adrian Y, Blumenfeld Jon, Liu Genyan, Michaeel Alber, Zhang Tuo, Robinson Brian D, Salvatore Steven P, Kapur Sandip, Donahue Stephanie, Bobb Warren O, Rennert Hanna

Abstract excerpt

Autosomal-dominant polycystic kidney disease (ADPKD) is caused by mutations in PKD1 and PKD2 and is characterized by proliferation of renal tubular epithelium and progressive chronic kidney disease. Derangements in similar cellular signaling pathways occur in ADPKD and renal malignancies, although an association of these disorders has not been established. Herein, we present a case of papillary RCC (pRCC)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26718059
DOI: 10.1016/j.cancergen.2015.11.002

Genes

MET
PKD1
PKD2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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