Article
The risk of clopidogrel resistance is associated with ABCB1 polymorphisms but not promoter methylation in a Chinese Han population.
PloS one - 1 Jan 2017
Su Jia, Yu Qinglin, Zhu Hao, Li Xiaojing, Cui Hanbin, Du Weiping, Ji Lindan, Tong Maoqing, Zheng Yibo, Xu Hongyu, Zhang Jianjiang, Zhu Yunyun, Xia Yezi, Liu Ting, Yao Qi, Yang Jun, Chen Xiaomin, Yu Jingbo
Abstract excerpt
The goal of our study was to investigate the contribution of ABCB1 expression to the risk of clopidogrel resistance (CR). Platelets functions were measured using the Verify-Now P2Y12 assay. Applying Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP), the single-nucleotide polymorphisms (SNPs) was tested. Using bisulphite pyrosequencing assay, we investigated the association of the ABCB1...
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