Article
Prevalence of factor H Binding Protein sub-variants among Neisseria meningitidis in China.
Vaccine - 25 Apr 2017
Shi Fenglin, Zhang Aiyu, Zhu Bingqing, Gao Yuan, Xu Li, Li Yixing, Yin Zundong, Li Junhong, Xie Na, Shao Zhujun
Abstract excerpt
OBJECTIVE: To study the prevalence of the fHbp genes in Neisseria meningitidis (N. meningitidis) isolates for further evaluation and development of serogroup B meningococcal vaccines in China. METHODS: A panel of 1012 N. meningitidis strains was selected from the national culture collection from 1956 to 2016, according to the years of isolation, locations, and strain sources. These were tested by FHbp variant...
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