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Factor H binding protein (FHbp): An evaluation of genotypic diversity across Neisseria meningitidis serogroups.

Human vaccines & immunotherapeutics - 31 Dec 2024

Li Zhenghui, Murthy Ashlesh Krishna, Hao Li, Andrew Lubomira, Anderson Annaliesa S

Abstract excerpt

Neisseria meningitidis serogroups A, B, C, W, X, and Y cause invasive meningococcal disease (IMD) worldwide. Factor H binding protein (FHbp), a key meningococcal virulence factor, is an antigen included in both licensed meningococcal serogroup B (MenB) vaccines. This review examines the biology and epidemiology of FHbp and assesses the ability and potential of FHbp vaccine antigens to protect against IMD. Using...

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Antigens, Bacterial
Bacterial Proteins
Meningococcal Infections
Meningococcal Vaccines
Multilocus Sequence Typing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neisseria meningitidis

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Identifiers

PMID: 39387286
DOI: 10.1080/21645515.2024.2409502
PMCID: PMC11469366

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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