Article
In silico serotyping of E. coli from short read data identifies limited novel O-loci but extensive diversity of O:H serotype combinations within and between pathogenic lineages.
Microbial genomics - 1 Jul 2016
Ingle Danielle J, Valcanis Mary, Kuzevski Alex, Tauschek Marija, Inouye Michael, Stinear Tim, Levine Myron M, Robins-Browne Roy M, Holt Kathryn E
Abstract excerpt
The lipopolysaccharide (O) and flagellar (H) surface antigens of Escherichia coli are targets for serotyping that have traditionally been used to identify pathogenic lineages. These surface antigens are important for the survival of E. coli within mammalian hosts. However, traditional serotyping has several limitations, and public health reference laboratories are increasingly moving towards whole genome...
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