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Highly Virulent Non-O157 Enterohemorrhagic Escherichia coli (EHEC) Serotypes Reflect Similar Phylogenetic Lineages, Providing New Insights into the Evolution of EHEC.

Applied and environmental microbiology - 1 Oct 2015

Eichhorn Inga, Heidemanns Katrin, Semmler Torsten, Kinnemann Bianca, Mellmann Alexander, Harmsen Dag, Anjum Muna F, Schmidt Herbert, Fruth Angelika, Valentin-Weigand Peter, Heesemann Jürgen, Suerbaum Sebastian, Karch Helge, Wieler Lothar H

Abstract excerpt

Enterohemorrhagic Escherichia coli (EHEC) is the causative agent of bloody diarrhea and extraintestinal sequelae in humans, most importantly hemolytic-uremic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP). Besides the bacteriophage-encoded Shiga toxin gene (stx), EHEC harbors the locus of enterocyte effacement (LEE), which confers the ability to cause attaching and effacing lesions. Currently, the...

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Identifiers

PMID: 26231647
DOI: 10.1128/AEM.01921-15
PMCID: PMC4579429

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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