Article
Q192R polymorphism of paraoxonase 1 gene associated with insulin resistance in Mexican children.
Archives of medical research - 1 Jan 2015
Alegría-Torres Jorge Alejandro, García-Domínguez María L, Cruz Miguel, Aradillas-García Celia
Abstract excerpt
BACKGROUND AND AIMS: The SNP rs662 in the paraoxonase 1 gene (PON1 Q192R) has been associated with obesity, dyslipidemia and cardiovascular risk. In this study, DNA samples of 117 children aged 6 to 12 years from San Luis Potosí, México were genotyped for Q192R polymorphism of the PON1 gene. METHODS: Genotypic frequencies were determined by allelic discrimination assay by real-time PCR using TaqMan fluorogenic...
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