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The genomic landscape of breast cancer and its interaction with host immunity

29 Sept 2016

Abstract excerpt

Molecular profiling of thousands of primary breast cancers has uncovered remarkable genomic diversity between breast cancer subtypes, and even within subtypes. Only a few driver genes are recurrently altered at high frequency highlighting great challenges for precision medicine. Considerable evidence also confirms the role of host immunosurveillance in influencing response to therapy and prognosis in HER2+ and...

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PMID: 27481651
DOI: 10.1016/j.breast.2016.07.015

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