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Immune-related gene data-based molecular subtyping related to the prognosis of breast cancer patients.

Breast cancer (Tokyo, Japan) - 1 Mar 2021

Mu Guoyu, Ji Hong, He Hui, Wang Hongjiang

Abstract excerpt

BACKGROUND: Breast cancer (BC), which is the most common malignant tumor in females, is associated with increasing morbidity and mortality. Effective treatments include surgery, chemotherapy, radiotherapy, endocrinotherapy and molecular-targeted therapy. With the development of molecular biology, immunology and pharmacogenomics, an increasing amount of evidence has shown that the infiltration of immune cells into...

Topics

Biomarkers, Tumor
Breast Neoplasms
Female
Gene Expression Regulation, Neoplastic
Humans
Kaplan-Meier Estimate
Phenotype
Prognosis
Signal Transduction
Transcriptome
Tumor Microenvironment

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Identifiers

PMID: 33245478
DOI: 10.1007/s12282-020-01191-z
PMCID: PMC7925489

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