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Advances in Pediatric Acute Promyelocytic Leukemia

2 Feb 2020

Abstract excerpt

Acute promyelocytic leukemia (APL) is a rare disease accounting for only 5%–10% of pediatric acute myeloid leukemia (AML) and fewer than 1000 cases occur annually in the United States across all age groups. Characterized by t (15; 17), with a resultant PML-RARA gene fusion driving leukemia development, advances in therapy have improved outcomes for APL significantly in the past several decades, now making APL the...

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PMID: 32024232
DOI: 10.3390/children7020011

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