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Article

Shared and Divergent Epigenetic Mechanisms in Cachexia and Sarcopenia

25 Jul 2022

Abstract excerpt

Significant loss of muscle mass may occur in cachexia and sarcopenia, which are major causes of mortality and disability. Cachexia represents a complex multi-organ syndrome associated with cancer and chronic diseases. It is often characterized by body weight loss, inflammation, and muscle and adipose wasting. Progressive muscle loss is also a hallmark of healthy aging, which is emerging worldwide as a main...

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PMID: 35892590
DOI: 10.3390/cells11152293

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