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Article

The circadian protein BMAL1 in myeloid cells is a negative regulator of allergic asthma

23 Mar 2017

Abstract excerpt

Our body clock drives rhythms in the expression of genes that have a 24-h periodicity. The transcription factor BMAL1 is a crucial component of the molecular clock. A number of physiological processes, including immune function, are modulated by the circadian clock. Asthma, a disease with very strong clinical evidence demonstrating regulation by circadian variation, is of particular relevance to circadian control...

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PMID: 28336811
DOI: 10.1152/ajplung.00072.2017

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